09 Cross-Linking Reagents

KMUS

KMUS

Cross-Linker

  • Product code
    K214  KMUS
  • CAS No.
    87981-04-2
  • Chemical name
    N-(11-Maleimidoundecanoyloxy)succinimide
  • MW
    C19H26N2O6=378.42
Unit size -- --

Cross-linking Reaction

Product Description

Hetero-bifunctional cross-linking reagents have activated esters and maleimide reactive groups. These functional groups react with amines and sulfhydryl groups of proteins, respectively. Enzyme-labeled haptens are prepared using hetero-bifunctional cross-linking reagents such as EMCS or GMBS. The cross-linking reaction requires neutral pH and mild temperature because it is necessary to maintain enzyme activity and antibody titers in the cross-linking reaction. Hetero-bifunctional cross-linking reagents with 3, 5, 7, or 10 linear carbon chains are available. These linear aliphatic chains act as spacers between the two reactive sites and their water-soluble reagents. They are more stable than the aromatic cross-linking reagents such as succinimidyl-4-N-maleimidobenzoate in a wider pH range.

Conjugation of Macromolecules with Hetero-Bifunctional Cross-Linking Reagent

Handling and storage condition

Specification
Appearance: White powder or crystalline powder
Purity (HPLC): ≧ 90.0 %
IR spectrum: Authentic
NMR spectrum: Authentic
Handling and storage condition
0-5°C
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Product Classification

Product Classification

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