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エイズからみた感染症研究の最前線


参考文献

1) A. J. McMichael and Rowland-Jones SL: Cellular immune responses to HIV. Nature , 2001, 410, 980.

2) S.G. Deeks and B. D. Walker, Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity , 2007, 27, 406.

3) P. K. Kiepiela, et al., CD8+ T-cell responses to different HIV proteins have discordant associations with viral load., Nat. Med., 2007, 13, 46.

4) T. Ueno, et al., Functionally impaired HIV-specific CD8 T cells show high affinity TCR-ligand interactions, J. Immunol., 2004, 173, 5451.

5) J. Fellay, et al., A whole genome association study of major determinants for host control of HIV-1, Science, 2007, 317, 944.

6) S. J. O’Brien, et al., HLA and AIDS: a cautionary tale, Trends Mol. Med., 2001, 7, 379.

7) T. Ueno, et al., Altering effects of antigenic variations in HIV-1 on antiviral effectiveness of HIV-specific CTLs, J. Immunol., 2007, 178, 5513.

8) Z. Brumme, et al., Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1, PLoS Pathog., 2007, 3, e94.

9) P. J. R. Goulder, D. I. Watkins, HIV and SIV CTL escape: implications for vaccine design, Nat. Rev. Immunol., 2004, 4, 630.

10) T. Ueno, et al., CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef, J. Immunol., 2008, 180, 1107.

11) A. J. Leslie, et al., HIV evolution: CTL escape mutation and reversion after transmission, Nat . Med., 2004, 10, 282.

12) M. A. Brockman, et al., Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A, J. Virol., 2007, 81, 12608.


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