Fig. 16 a) Chemical structures of a hydrogelator 3 and as an additional component, an amphiphilic carboxylic acid derivative 11 bearing the hydrophobic parts of 3.

b) Photographs of a typical example of the pH‐responsive volume phase transition of the mixed hydrogel (equal quantities of 3 and 11) before and after shrinkage.

c) Schematic illustration of the two-component gel strategy, and the subsequent pH-responsive volume change.

d) The amount of five distinct substrates released after 60 min for vitamin B1, vitamin B6, vitamin B12 (hydrophilic substances), quercetin and myricetin (hydrophobic flavone derivatives).


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