[参考文献]
1) M. Nishida, T. Sawa, N. Kitajima et al., “Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration”, Nat. Chem. Biol., 2012, 8, 714-724.
2) T. Ida, T. Sawa, H. Ihara et al., “Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling”, Proc. Natl. Acad. Sci. U S A, 2014, 111, 7606-7611.
3) L. Hayflick, “The serial cultivation of human diploid cell strains”, Exp. Cell Res., 1961, 585-621.
4) D. P. Jones, “Redox theory of aging”, Redox Biol., 2015, 5, 71-79.
5) M. Nishida, A. Nishimura, T. Matsunaga et al., “Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells”, Free Radic. Biol. Med., 2017, 109, 132-140.
6) M. Nishida, T. Toyama and T. Akaike, “Role of 8-nitro-cGMP and its redox regulation in cardiovascular electrophilic signaling”, J. Mol. Cell Cardiol., 2014, 73, 10-17.
7) B. D. Paul and S. H. Snyder, “H2S signalling through protein sulfhydration and beyond”, Nat. Rev. Mol. Cell Biol., 2012, 13, 499-507.
8) C. Hine, E. Harputlugil, Y. Zhang et al., “Endogenous hydrogen sulfide production is essential for dietary restriction benefits”, Cell, 2015, 160, 132-144.
9) A. Longchamp, T. Mirabella, A. Arduini et al., “Amino acid restriction triggers angiogenesis via GCN2/ATF4 regulation of VEGF and H2S production” Cell, 2018, 173, 117-129.
10) A. Das, G. X. Huang and M. S. Bonkowski et al., “Impairmen to fan endothelial NAD+-H2S signaling network is a reversible cause of vascular aging”, Cell, 2018, 173, 74-89.
11) T. Akaike, T. Ida, F. Y. Wei, M. Nishida et al., “Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics”, Nat. Commun., 2017, 8, 1177.
12) D. H. Cho, T. Nakamura, J. Fang et al., “S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury”, Science, 2009, 324, 102-105.
13) M. Song and G. W. II Dorn, “Mitoconfusion: noncanonical functioning of dynamism factors in static mitochondria of the heart”, Cell Metab., 2015, 21, 195-205.
14) N. S. Rajasekaran et al., “Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice”, Cell, 2007, 130, 427-439.
15) J. Li et al., “Nrf2 protects against maladaptive cardiac responses to hemodynamic stress”, Arterioscler. Thromb. Vasc. Biol., 2009, 29, 1843-1850.
16) N. S. Rajasekaran et al., “Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice”, Antioxid. Redox Signal., 2011, 14, 957-971.
17) H. C. Chang et al., “Getting to the heart of cardiac disease by decreasing mitochondrial iron”, Circ. Res., 2016, 119, 1164-1166.
18) É. Dóka, I. Pader, A. Biro et al., “A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredox in and glutathione systems”, Sci. Adv., 2016, 2 : e1500968.