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siRNA 選択性蛍光プローブを用いた細胞内デリバリーイメージング解析

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4) A. Gallas, C. Alexander, M. C. Davies, S. Puri and S. Allen, “Chemistry and formulations for siRNA therapeutics”, Chem. Soc., Rev., 2013, 42, 7983-7997.

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12) A. Järve, J. Müller, I.-H. Kim, K. Rohr, C. MacLean, G. Fricker, U. Massing, F. Eberle, A. Dalpke, R. Fischer, M. F. Trendelenburg and M. Helm, “Surveillance of siRNA integrity by FRET imaging”, Nucl. Acids Res., 2007, 35, e124.

13) A. S. Wahba, F. Azizi, G. F. Deleavey, C. Brown, F. Robert, M. Carrier, A. Kalota, A. M. Gewirtz, J. Pelletier, R. H. E. Hudson and M. J. Damha, “Phenylpyrrolocytosine as an unobtrusive base modification for monitoring activity and cellular trafficking of siRNA”, ACS Chem. Biol., 2011, 6, 912-919.

14) Y. Kamiya, A. Ito, H. Ito, M. Urushihara, J. Takai, T. Fujii, X. Liang, H. Kashida and H. Asanuma, “Selective labeling of mature RISC using siRNA carrying fluorophore-quencher pair”, Chem. Sci., 2013, 4, 4016-4021.

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16) T. Sato, Y. Sato, K. Iwai, S. Kuge, S. Nishizawa and N. Teramae, “Synthetic fluorescent probes capable of selective recognition of 3’-overhanging nucleotides for siRNA delivery imaging”, Chem. Commun., 2015, 51, 1421-1424.

17) T. Sato, Y. Sato, K. Iwai, S. Kuge, N. Teramae and S. Nishizawa, “Fluorescence imaging of siRNA delivery by peptide nucleic acid-based probe”, Anal. Sci., 2015, 31, 315-320.

18) C. A. Alabi, K. T. Love, G. Sahay, T. Stutzman, W. T. Young, R. Langer and D. G. Anderson, “FRET-labeled siRNA probes for tracking assembly and disassembly of siRNA nanocomplexes”, ACS Nano, 2012, 6, 6133-6141.

19) H. Hong, Y. Zhang and W. Cai, “In vivo imaging of RNA interference”, J. Nucl. Med., 2010, 51, 169-172.

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