エピジェネティクス機構による細胞状態とリプログラミング

参考文献

1） 中尾光善，エピジェネティクス医科学，実験医学（増刊号）, 2006, 24, 1038-1044.

2） 中尾光善，疾患エピジェネティクスの新展開，細胞工学, 2009, 28, 522-527.

3） T. Mishiro, K. Ishihara, S. Hino, S. Tsutsumi, H. Aburatani, K. Shirahige, Y. Kinoshita, M. Nakao, Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster, EMBO J., 2009, 28, 1234-1245.

4） K. S. Wendt, K. Yoshida, T. Itoh, M. Bando, B. Koch, E. Schirghuber, S. Tsutsumi, G. Nagae, K. Ishihara, T. Mishiro, K. Yahata, F. Imamoto, H. Aburatani, M. Nakao, N. Imamoto, K. Maeshima, K. Shirahige, J. M. Peters, Cohesin mediates transcriptional insulation by CCCTC-binding factor, Nature., 2008, 451, 796-803.

5） K. Ishihara, M. Oshimura, M. Nakao, CTCF-dependent chromatin insulator is linked to epigenetic remodeling, Mol. Cell., 2006, 23, 733-742.

6） N. Sasai, M. Nakao, P. A. Defossez, Sequence-specific recognition of methylated DNA by human zinc-finger proteins, Nucleic Acids Res., 2010, 38, 5015-5022.

7） Y. Sakamoto, S. Watanabe, T. Ichimura, M. Kawasuji, H. Koseki, H. Baba, M. Nakao, Overlapping roles of the methylated DNA binding protein MBD1 and polycomb group proteins in transcriptional repression of HoxA genes and heterochromatin foci formation, J. Biol. Chem., 2007, 282, 16391-16400.

8） L. Liu, K. Ishihara, T. Ichimura, N. Fujita, S. Hino, S. Tomita, S. Watanabe, N. Saitoh, T. Ito, M. Nakao, MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity, J. Biol. Chem., 2009, 284, 5165-5174.

9） S. Watanabe, Y. Ueda, S. Akaboshi, Y. Hino, Y. Sekita, M. Nakao, HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cells, Am. J. Pathol., 2009, 174, 854-868.

10） S. Akaboshi, S. Watanabe, Y. Hino, Y. Sekita, K. Araki, K. Yamamura, M. Oshima, T. Ito, H. Baba, M. Nakao, HMGA1 is induced by Wnt/β-catenin pathway and maintains cell proliferation in gastric cancer, Am. J. Pathol., 2009, 175, 1675-1685.

11） Y. Ueda, S. Watanabe, S. Tei, N. Saitoh, J. Kuratsu, M. Nakao, The high mobility group protein HMGA1 inhibits retinoblastoma protein-mediated cellular G0 arrest, Cancer Sci., 2007, 98, 1893-1901.

12） T. Aoto, N. Saitoh, T. Ichimura, H. Niwa, M. Nakao, Nuclear and chromatin reorganization in the MHC-Oct3/4 locus at developmental phases of embryonic stem cell differentiation, Dev. Biol., 2006, 298, 345-367.

13） M. F. Fraga, E. Ballestar, M. F. Paz, S. Ropero, F. Setien, M. L. Ballestar, D. Heine-Suñer, J. C. Cigudosa, M. Urioste, J. Benitez, M. Boix-Chornet, A. Sanchez-Aguilera, C. Ling, E. Carlsson, P. Poulsen, A. Vaag, Z. Stephan, T. D. Spector, Y. Z. Wu, C. Plass, M. Esteller, Epigenetic differences arise during the lifetime of monozygotic twins, Proc. Natl. Acad. Sci. USA, 2005, 102, 10604-10609.

14） G. L. Wolff, G. L. Wolff, R. L. Kodell, S. R. Moore, C. A. Cooney, Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/amice, FASEB J., 1998, 12, 949-957.

15） K. Tateishi, Y. Okada, E. M. Kallin, Y. Zhang, Role of Jhdm2a in regulating metabolic gene expression and obesity resistance, Nature, 2009, 458, 757-761.

16） 日野信次朗，坂元顕久，中尾光善，エネルギー代謝病のエピジェネティクス、疾患エピジェネティクスの新展開，細胞工学, 2009, 28, 535-540.

17） D. J. P. Barker, P. D. Winter, C. Osmond, B. Margetts, S. J. Simmonds, Weight in infancy and death from ischaemic heart disease, Lancet, 1989, 2, 577-580.

18） D. J. P. Barker, The origins of the developmental origins theory, J. Intern. Med., 2007, 261, 412-417.

19） 中尾光善，細胞核と機能ドメイン、細胞核再発見：解明が進む機能ドメインとその役割，細胞工学, 2002, 21, 1138-1142.

20） N. Saitoh, Y. Uchimura, T. Tachibana, S. Sugahara, H. Saitoh, M. Nakao, In situ SUMOylation analysis reveals a modulatory role of RanBP2 in the nuclear rim and PML bodies, Exp. Cell Res., 2006, 312, 1418-1430.