GABA合成酵素グルタミン酸デカルボキシラーゼにみる隠れた機能:味覚での役割と応用
参考文献
1)J. Awapara, A. J. Landua, R. Fuerst, B. Seale, Free γ-aminobutyric acid in
brain, J. Biol. Chem ., 1950,187 , 35-39.
2) E. Roberts, S. Frankel, γ-Aminobutyric acid in brain: Its formation from
glutamic acid, J. Biol. Chem ., 1950, 187 , 56-63.
3) E. Roberts, S. Frankel, Glutamic acid decarboxylase in brain, J. Biol.Chem. , 1951, 188 , 789-95.
4)T. Matsumoto, I. Yamaura, M. Funatsu, Physical properties of glutamate
decarboxylase from squash, Agric. Bio. Chem., 1990, 54 , 3001-03.
5) M. G. Erlander, N. J. K. Tillakaratne, S. Feldblum, N. Patel, A. J. Tobin, Two
genes encode distinct glutamate decarboxylases, Neuron , 1991, 7 , 91-100.
6) S. Baekkeskov, H-J. Aanstoot, S. Christgau, A. Reetz, M. Solimena, M.
Cascalho, et al ., Identifi cation of the 64K autoantigen in insulin-dependent
diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase,
Nature , 1990, 347 , 151-56.
7) H. Ueno, Enzymatic and structural aspects on glutamate decarboxylase, J.Mol. Catalysis B.: Enzymatic , 2000, 10 , 67-79.
8) G. Fenalti, R. H. Law, A. M. Buckle, C. Langendorf, K. Tuck, C. J. Rosado,
et al ., GABA production by glutamic acid decarboxylase is regulated by a
dynamic catalytic loop, Nat. Struct. Mol. Biol ., 2007, 14 (4), 280-6.
9) S. Christgau, H-J. Aanstoot, H. Schierbeck, K. Begley, S. Tullin, K. Hejnaes,
et al ., Membrane anchoring of the autoantigen GAD65 to microvesicles in
pancreatic β-cells by palmitoylation in the NH2-terminal domain, J. Cell.
Biol, 1992, 118 , 309-20.
10) Y. Shi, B. Veit, S. Baekkeskov, Amino acid residues 24-31 but not
palmitoylation of cysteines 30 and 45 are required for membrane anchoring
of glutamic acid decarboxylase, GAD65, J. Cell. Biol. , 1994, 124 (6), 927-34.
11) J. Wei, J.Y. Wu, Post-translational Regulation of L -Glutamic Acid
Decarboxylase in the Brain, Neurochemical research, 2008.
12)M. Namchuk, L. Lindsay, C. W. Turck, J. Kanaani, S. Baekkeskov,
Phosphorylation of serine residues 3, 6, 10, and 13 distinguishes
membrane anchored from soluble glutamic acid decarboxylase 65 and isrestricted to glutamic acid decarboxylase 65α, J. Biol. Chem ., 1997, 272(3), 1548-57.
13) H. Asada, Y. Kawamura, K. Maruyama, H. Kume, R-G. Ding, N. Kanbara,
et al ., Cleft palate and decreased brain γ-aminobutyric acid in mice lacking
the 67-kDa isoform of glutamic acid decarboxylase, Proc Natl. Acad. Sci.
USA , 1997, 94 , 6496-99.
14) H. Asada, Y. Kawamura, K. Maruyama, H. Kume, R-G. Ding, F. Y. Ji,
et al ., Mice lacking the 65 kDa isoform of glutamic acid decarboxylase
(GAD65) maintain normal levels of GAD67 and GABA in their brains but
are susceptible to seizures, Biochem. Biophys. Res. Commun ., 1996, 229 ,
891-95.
15) A. Tramonti, M. De Canio, Delany I, Scarlato V, D. De Biase, Mechanisms
of transcription activation exerted by GadX and GadW at the gadA and
gadBC gene promoters of the glutamate-based acid resistance system in
Escherichia coli , J. Bacteriol ., 2006, 188 (23), 8118-27.
16) N. Stewart, J. Feng, X. Liu, D. Chaudhuri, J. W. Foster, M. Drolet, et al .,
Loss of topoisomerase I function affects the RpoS-dependent and GAD
systems of acid resistance in Escherichia coli , Microbiology , 2005, 151 (Pt8), 2783-91.
17) G. Capitani, D. De Biase, C. Aurizi, H. Gut, F. Bossa, M. G. Grutter,
Crystal structure and functional analysis of Escherichia coli glutamate
decarboxylase, EMBO J . , 2003, 22 (16), 4027-37.
18) S. T. Coleman, T. K. Fang, S. A. Rovinsky, F. J. Turano, W. S. Moye-
Rowley, Expression of a glutamate decarboxylase homologue is required
for normal oxidative stress tolerance in Saccharomyces cerevisiae , J. Biol.
Chem ., 2001, 276 (1), 244-50.
19) K. Ito, K. Tanaka, Y. Nishibe, J. Hasegawa, H. Ueno, GABA-synthesizing
enzyme, GAD67, from dermal fi broblasts: evidence for a new skin function,
Biochim. Biophys. Acta ., 2007,1770 (2), 291-6.
20) K. Akamatsu, Y. Nakamura, H. Hayasaki, K. Kanabara, K. Maemura,
Y. Yanagawa, et al ., Cells expressing GABA synthetic enzyme,
glutamate decarboxylase, in stomach and intestine: RT-PCR and
immunohistochemistry studies, J. Biol. Macromol . , 2007, 7 , 55-62.
21) M. Iwahori, K. Akamatsu, S. Kurohara, K. Yokoigawa, H. Ueno, H.
Ogawa, et al ., Immunohistochemical study of the localization of
glutamate decarboxylase in rodent's submandibular gland, J. Biol.
Macromol ., 2002, 2 , 76-77.
22) K. Ito, Y. Katsuyama, N. Banno, J. Hasegawa, H. Ueno, Localization
and characterization of glutamate decarboxylase in the skin, XXI IFSCC
International Congressed , 2002, 102.
23) K. Obata, GABAergic neurons revealed in the gene knock-out and knockin
mice, Tanpakushitsu kakusan koso 2004, 49 (3 Suppl), 295-300.
24) N. Tamamaki, Y. Yanagawa, R. Tomioka, J. Miyazaki, K. Obata, T.
Kaneko, Green fluorescent protein expression and colocalization with
calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in
mouse, J. Comp. Neurol ., 2003, 467 (1), 60-79.
25) K. Abe, Studies on taste: molecular biology and food science, Biosci.
Biotechnol. Biochem ., 2008, 72 (7), 1647-56.
26) Y. Ninomiya, 食の調節情報としての味覚とおいしさのシグナリング. 化
学と生物, 2007, 45 (6), 419-25
27) Y. Nakamura, Y. Yanagawa, K. Obata, M. Watanabe, H. Ueno, GABA is
produced in taste bud, Chem. Senses , 2007, 32 , J19.
28) Y. Nakamura, Y. Yanagawa, K. Obata, M. Watanabe, H. Ueno, GABA is
produced in taste bud, 40th Annual Meeting of the Japanese Association
for the Study of Taste and Smell (JASTS XL)ed, Fukuoka, Japan: Chem.
Senses , 2007, J1-J25 (No. 69).
29)K. Wada, Y. Nitta, H. Ueno, Effect of GABA on taste sensory as judged
by taste test, 家政学研究(奈良), 2006, 53 (1), 1-6.
30) K. Hisaki, K. Wada, K. Shinohara, Y. Nakamura, H. Ueno, Contribution of
GABA to taste sensation evaluated by taste test and effect of compounds
in spices on the activity of GABA synthetic enzyme, Japanese Taste and
Smell J ., 2007, 14 (3): 435-38.
31) H. Ueno, K. Akamatsu, K. Yoshioka, S. Kurohara, M. Iwahori, K. Tone,
et al ., Study of regulatory properties of spice and herb extracts on
glutamate decarboxylase and site-specific expression of glutamate
decarboxylase in digestive system, Proceedings of 3rd China-Japan
International Conference on Vitamins , 2004, 146-56.
32) S. Kurohara, M. Asai, M. Hayashi, K. Yokoigawa, H. Ueno, Microanalysis
of GABA: An application for evaluating GABA production in yeast strains
and the effect of spice extracts on glutamate decarboxylase activity, J.
Biol. Macromol ., 2001, 1 , 45-48.
|